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Based on the information available, there are over-the-counter (OTC) alternatives that can help reduce cholesterol levels, but it is important to note that their potency may not be as high as that of prescription drugs such as Lipitor. Lipitor, also known as atorvastatin, is a potent statin that works by blocking a substance your body needs to make cholesterol [1].

While OTC options may not match Lipitor's potency, they can still contribute to lowering cholesterol levels when used in combination with a healthy lifestyle. These alternatives primarily include various dietary supplements and functional foods.

Some OTC supplements that can help reduce cholesterol are:

1. Plant sterols and stanols: These naturally occur in small amounts in various fruits, vegetables, nuts, and grains. They can also be found in supplements and functional foods, such as margarine and orange juice. According to the FDA, consuming 1.3 grams of plant sterols and stanols per day can lower LDL cholesterol by 6-15% [2].

2. Red yeast rice: This is a dietary supplement made by fermenting red yeast (Monascus purpureus) with rice. It contains a variety of compounds, including monacolin K, which is structurally similar to lovastatin (a prescription medication used to treat high cholesterol) [3]. However, the FDA has cautioned against using red yeast rice products due to inconsistent amounts of monacolin K and potential contamination with citrinin, a toxin that can damage the kidneys [4].

3. Fish oil (omega-3 fatty acids): While primarily known for their heart health benefits, omega-3 fatty acids may also help lower triglyceride levels [5].

4. Garlic: Some studies suggest that garlic may help lower total and LDL cholesterol levels slightly [6].

It is crucial to consult a healthcare professional before starting any new supplement regimen, especially when already taking prescription medications. Maintaining a heart-healthy lifestyle, including a balanced diet and regular exercise, is essential for managing cholesterol levels.

Sources:

1. Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20063084>
2. FDA. (2019). Questions and Answers: Plant Sterol and Stanol Esters. Retrieved from <https://www.fda.gov/food/ingredients-additives-gras-packaging-glance/questions-and-answers-plant-sterol-and-stanol-esters>
3. NCCIH. (2021). Red Yeast Rice. Retrieved from <https://www.nccih.nih.gov/health/red-yeast-rice>
4. FDA. (2019). FDA Warns Consumers About Serious Health Risks Associated with Red Yeast Rice Products. Retrieved from <https://www.fda.gov/news-events/press-announcements/fda-warns-consumers-about-serious-health-risks-associated-red-yeast-rice-products>
5. Mayo Clinic. (2021). Omega-3 Fatty Acids. Retrieved from <https://www.mayoclinic.org/drugs-supplements-omega-3-fatty-acids/art-20364775>
6. Cleveland Clinic. (2021). Garlic: A Natural Wonder. Retrieved from <https://my.clevelandclinic.org/health/articles/17456-garlic-a-natural-wonder>
7. DrugPatentWatch.com. (n.d.). Atorvastatin Calcium. Retrieved from <https://www.drugpatentwatch.com/drugs/atorvastatin-calcium>