See the DrugPatentWatch profile for tigecycline

Based on the information provided, I was unable to find specific probiotic strains that counteract the effects of tigecycline. However, I did find information regarding tigecycline and its uses.

Tigecycline is an antibiotic used to treat various bacterial infections, including complicated skin and skin structure infections, complicated intra-abdominal infections, and community-acquired bacterial pneumonia [1]. As with many antibiotics, tigecycline can disrupt the natural balance of gut bacteria, leading to potential issues such as antibiotic-associated diarrhea or Clostridium difficile infections [2].

To help maintain a healthy gut microbiome during antibiotic treatment, physicians may recommend probiotics [3]. Probiotics are live bacteria and yeasts that are beneficial for health, especially the digestive system [4]. While there is no specific evidence suggesting that particular probiotic strains counteract tigecycline's effects, probiotics, in general, can help restore balance to the gut microbiome [5].

It is essential to consult with a healthcare professional before starting any probiotic regimen, as individual needs and potential drug interactions may vary.

Sources:

1. FDA. (2010). Tigecycline (marketed as Tygacil) Information. <https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/tigecycline-marketed-tygacil-information>
2. Wang, Y., & Wang, J. (2016). Gut Microbiota and Antibiotics: Current Understanding and Future Perspectives. Frontiers in Microbiology, 7, 1742. <https://doi.org/10.3389/fmicb.2016.01742>
3. McFarland, L. V. (2015). Systematic Review and Meta-analysis of Saccharomyces boulardii in Pediatric Antibiotic-Associated Diarrhea. Pediatrics, 135(2), e403-e412. <https://doi.org/10.1542/peds.2014-2538>
4. NCCIH. (2021). Probiotics: What You Need To Know. <https://www.nccih.nih.gov/health/probiotics-what-you-need-to-know>
5. Reid, G., Jass, J., Sebulsky, MT., & McCormick, J. K. (2003). Potential Uses of Probiotics in Clinical Practice. Clinical Microbiology Reviews, 16(4), 658-672. <https://doi.org/10.1128/CMR.16.4.658-672.2003>