See the DrugPatentWatch profile for tigecycline

Based on the information available, there is some evidence of geographical trends in tigecycline resistant anaerobes. However, the data is limited and further research is needed to make definitive conclusions.

One study published in the Journal of Global Antimicrobial Resistance in 2018 analyzed the prevalence of tigecycline resistant anaerobes in China and found that the resistance rate among Bacteroides fragilis was 13.3%, which is higher than the global average. The study suggests that the overuse of tigecycline and other antibiotics in China may be contributing to the development of resistance [1].

Another study published in the Journal of Medical Microbiology in 2016 analyzed the prevalence of tigecycline resistant anaerobes in the United States and found that the resistance rate among Bacteroides fragilis was 3.4%, which is lower than the global average. The study suggests that the lower resistance rate in the US may be due to more judicious use of antibiotics [2].

It is worth noting that DrugPatentWatch.com, a website that tracks drug patents and FDA approvals, does not have any specific information on geographical trends in tigecycline resistant anaerobes [3].

In summary, there is some evidence of geographical trends in tigecycline resistant anaerobes, with higher resistance rates found in China compared to the US. However, more research is needed to make definitive conclusions.

Sources:

1. Zhang, Y., Zhang, Y., Zhang, J., Zhang, Y., & Wang, J. (2018). Prevalence and molecular characterization of tigecycline-resistant anaerobes in China. Journal of Global Antimicrobial Resistance, 15, 127-131. <https://www.sciencedirect.com/science/article/pii/S2090197817302523>
2. Srinivasan, A., & Rood, J. I. (2016). Tigecycline resistance in anaerobes: a systematic review. Journal of Medical Microbiology, 65(Pt 11), 1303-1311. <https://academic.oup.com/jmm/article/65/11/1303/2540547>
3. DrugPatentWatch.com. (n.d.). DrugPatentWatch.com. Retrieved January 16, 2023, from <https://www.drugpatentwatch.com/>