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Common Side Effects of Keytruda: What You Need to Know

What is Keytruda?

Keytruda, also known as pembrolizumab, is a medication used to treat various types of cancer, including melanoma, lung cancer, and classical Hodgkin lymphoma. It is a type of immunotherapy that works by boosting the body's natural defenses to fight cancer cells.

Common Side Effects of Keytruda

While Keytruda has shown promising results in treating cancer, it can cause a range of side effects. Some of the most common side effects of Keytruda include:

Fatigue

Fatigue is one of the most common side effects of Keytruda, affecting up to 70% of patients. This can range from mild to severe and can make everyday activities feel exhausting.

Diarrhea

Diarrhea is another common side effect of Keytruda, affecting up to 40% of patients. This can range from mild to severe and can lead to dehydration if not managed properly.

Nausea and Vomiting

Nausea and vomiting are common side effects of Keytruda, affecting up to 30% of patients. These symptoms can be managed with medication and dietary changes.

Rash

Rash is a common side effect of Keytruda, affecting up to 20% of patients. This can range from mild to severe and can be itchy or painful.

Itching

Itching is another common side effect of Keytruda, affecting up to 15% of patients. This can range from mild to severe and can be managed with antihistamines and topical creams.

Cough

Cough is a common side effect of Keytruda, affecting up to 10% of patients. This can range from mild to severe and can be managed with cough medication and rest.

Shortness of Breath

Shortness of breath is a less common side effect of Keytruda, affecting up to 5% of patients. This can range from mild to severe and can be managed with oxygen therapy and rest.

Less Common but Serious Side Effects

While the above side effects are common, Keytruda can also cause less common but serious side effects, including:

Immune-Mediated Adverse Reactions

Immune-mediated adverse reactions are a rare but serious side effect of Keytruda, affecting up to 1% of patients. These reactions can include inflammation of the lungs, liver, or kidneys, and can be life-threatening.

Pneumonitis

Pneumonitis is a rare but serious side effect of Keytruda, affecting up to 1% of patients. This is an inflammation of the lungs that can be life-threatening.

Managing Side Effects

While side effects of Keytruda can be uncomfortable, they can often be managed with medication and lifestyle changes. It is essential to discuss any side effects with your healthcare provider and follow their guidance on managing them.

Conclusion

Keytruda is a powerful medication that has shown promising results in treating various types of cancer. While it can cause a range of side effects, many of these can be managed with medication and lifestyle changes. It is essential to discuss any side effects with your healthcare provider and follow their guidance on managing them.

Frequently Asked Questions

Q: What are the most common side effects of Keytruda?
A: The most common side effects of Keytruda include fatigue, diarrhea, nausea and vomiting, rash, itching, cough, and shortness of breath.

Q: How common are immune-mediated adverse reactions with Keytruda?
A: Immune-mediated adverse reactions are a rare but serious side effect of Keytruda, affecting up to 1% of patients.

Q: Can side effects of Keytruda be managed?
A: Yes, many side effects of Keytruda can be managed with medication and lifestyle changes.

Q: What should I do if I experience side effects from Keytruda?
A: If you experience side effects from Keytruda, it is essential to discuss them with your healthcare provider and follow their guidance on managing them.

Q: Can I continue taking Keytruda if I experience side effects?
A: It depends on the severity and type of side effects you are experiencing. Your healthcare provider will assess the situation and determine whether it is safe to continue taking Keytruda.

Cited Sources:

1. National Cancer Institute. (2022). Pembrolizumab. Retrieved from <https://www.cancer.gov/about-cancer/treatment/types/immunotherapy/pembrolizumab>
2. Merck & Co., Inc. (2022). Keytruda Prescribing Information. Retrieved from <https://www.merck.com/product/usa/picirculars/k/keytruda/keytrudapi.pdf>
3. DrugPatentWatch.com. (2022). Pembrolizumab (Keytruda) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration/pembrolizumab-keytruda>

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