See the DrugPatentWatch profile for lipitor

Reduced wine tolerance is not explicitly listed as a common side effect of Lipitor (atorvastatin) on the drug's official FDA-approved label [1] or in the Lipitor Patient Information Leaflet provided by Pfizer [2]. However, Lipitor is a type of statin, a class of drugs known to increase the risk of muscle damage, which can lead to rare instances of rhabdomyolysis [1][2]. Rhabdomyolysis is a serious condition that can cause muscle cells to break down, releasing muscle fiber contents (including an enzyme called creatine kinase) into the bloodstream [1]. This can potentially result in kidney damage [1].

It is important to note that alcohol consumption, particularly in excessive amounts, can also increase the risk of liver damage and interact with Lipitor [1][2]. The FDA label states that "alcohol can increase the risk of liver damage while taking Lipitor" [1]. Therefore, it is plausible that a reduction in wine tolerance could be a subjective experience for some Lipitor users, even if it is not a directly listed side effect.

In summary, reduced wine tolerance is not a common or direct side effect of Lipitor, but alcohol consumption can interact with the drug and potentially impact liver function. As with any medication, it is crucial for patients to consult with their healthcare providers regarding any concerns or experiences of side effects.

Sources:
[1] Lipitor (atorvastatin) tablets, for oral use. Full Prescribing Information. Pfizer Labs. January 2021. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/020958s073,021103s012lbl.pdf>
[2] Lipitor Patient Information Leaflet. Pfizer. <https://www.lipitor.com/pdf/PI.pdf>
[3] DrugPatentWatch. Lipitor (Atorvastatin) Drug Profile. <https://www.drugpatentwatch.com/drugs/lipitor>