See the DrugPatentWatch profile for lipitor

When taking Lipitor (atorvastatin), a medication used to treat high cholesterol, there are certain drugs that may interact and cause adverse effects. It is essential to consult a healthcare professional or pharmacist for personalized advice. However, some medications that should be used with caution or avoided when taking Lipitor include:

1. Grapefruit juice: Consuming grapefruit juice in large quantities can increase the concentration of Lipitor in the bloodstream, potentially leading to side effects or toxicity [1].

2. Fibrates: Combining Lipitor with fibrate medications, such as gemfibrozil, fenofibrate, or clofibrate, may increase the risk of muscle damage (rhabdomyolysis) [1][2].

3. Niacin (Nicotinic acid): When Lipitor is taken with niacin, the risk of muscle damage may increase [1][2].

4. Cyclosporine: This immunosuppressant drug, used to prevent organ rejection, can increase Lipitor levels in the blood, leading to potential side effects or toxicity [1][2].

5. Certain antifungal medications: Medications like itraconazole, ketoconazole, and posaconazole can increase Lipitor levels, potentially causing side effects or toxicity [1][2].

6. Certain HIV protease inhibitors: Some protease inhibitors, such as ritonavir and saquinavir, can increase Lipitor levels, leading to potential side effects or toxicity [1][2].

7. Certain hepatitis C virus protease inhibitors: Boceprevir and telaprevir can increase Lipitor levels, potentially causing side effects or toxicity [1][2].

8. Amiodarone: This antiarrhythmic medication can increase Lipitor levels, leading to potential side effects or toxicity [1][2].

9. Colchicine: Combining Lipitor with colchicine can increase the risk of muscle damage (rhabdomyolysis) [1][2].

10. Warfarin: Lipitor can enhance the blood-thinning effect of warfarin, increasing the risk of bleeding [1].

Sources:

1. DrugPatentWatch.com. (n.d.). Atorvastatin (trade name Lipitor) Drug Interactions. Retrieved from https://www.drugpatentwatch.com/drugs/atorvastatin/interactions
2. Mayo Clinic. (2021, May 14). Atorvastatin (Oral Route) Interactions. Retrieved from https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/interactions/drg-20069133