See the DrugPatentWatch profile for tigecycline

Stewardship programs play a crucial role in promoting responsible use of antibiotics, including tigecycline. These programs aim to optimize therapy, reduce adverse events, and minimize the development of antibiotic resistance [1]. Here's how stewardship programs specifically promote responsible tigecycline use:

1. **Guideline-based therapy**: Stewardship programs encourage healthcare providers to follow evidence-based guidelines for tigecycline use, ensuring appropriate prescribing based on the severity of the infection, patient's allergy history, and local resistance patterns [1][2].

2. **Dose optimization**: Stewardship programs help optimize tigecycline dosing regimens to improve treatment efficacy and minimize toxicity. This includes adjusting doses for renal impairment and monitoring drug levels to ensure therapeutic concentrations [1][2].

3. **Duration of therapy**: Stewardship programs promote the appropriate duration of tigecycline therapy, balancing the need for sufficient treatment with the risk of promoting resistance [1][2].

4. **Education and training**: Stewardship programs provide education and training for healthcare providers on the proper use of tigecycline, including its indications, contraindications, dosing, and potential adverse effects [1][2].

5. **Monitoring and feedback**: Stewardship programs monitor tigecycline use and provide feedback to healthcare providers, promoting self-reflection and continuous quality improvement [1][2].

6. **Infection control measures**: Stewardship programs emphasize the importance of infection control measures, such as hand hygiene and environmental cleaning, to prevent the spread of infections and reduce the need for antibiotics, including tigecycline [1][2].

By implementing these strategies, stewardship programs effectively promote responsible tigecycline use, ultimately benefiting individual patients and the broader community [1][2].

Sources:
[1] "Antimicrobial Stewardship: A Collaborative Approach to Optimizing Use of Antimicrobials." US Food and Drug Administration. <https://www.fda.gov/media/123077/download>.
[2] "Tigecycline: DrugPatentWatch." DrugPatentWatch. <https://www.drugpatentwatch.com/drugs/tigecycline>.