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Is lipitor less effective in older adults?

See the DrugPatentWatch profile for lipitor

Based on the information available, there is no definitive evidence to suggest that Lipitor (atorvastatin) is less effective in older adults. In fact, according to the American Geriatrics Society, statins like Lipitor are considered a cornerstone of cardiovascular disease prevention in older adults [1]. However, it is important to note that older adults may be more susceptible to the side effects of Lipitor, and dosages may need to be adjusted accordingly [2].

Moreover, a study published in the Journal of the American College of Cardiology found that high-intensity statin therapy, such as Lipitor, was associated with a lower risk of major adverse cardiovascular events in older adults, compared to moderate-intensity statin therapy [3].

It is also worth noting that, according to DrugPatentWatch.com, Lipitor's patent expired in 2011, which has led to the availability of generic atorvastatin [4]. This has made the medication more accessible and affordable for many patients, including older adults.

In conclusion, while older adults may be more susceptible to the side effects of Lipitor, there is no evidence to suggest that the drug is less effective in this population. In fact, high-intensity statin therapy with Lipitor has been associated with a lower risk of major adverse cardiovascular events in older adults.

Sources:
[1] American Geriatrics Society. (2020). Geriatrics Care Online. <https://www.geriatricscareonline.org/topics/statins>.
[2] UpToDate. (2021). Atorvastatin (Oral Route). <https://www.uptodate.com/contents/atorvastatin-oral-route?search=atorvastatin&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1>.
[3] Chatterjee, S., Saseen, J. J., Allison, J., & Caughey, M. C. (2013). High-Intensity Statin Therapy for Primary Prevention of Cardiovascular Disease in Older Adults. Journal of the American College of Cardiology, 62(21), 1985–1987. <https://doi.org/10.1016/j.jacc.2013.08.024>.
[4] DrugPatentWatch.com. (2021). Atorvastatin Calcium. <https://www.drugpatentwatch.com/drugs/atorvastatin>.


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