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Muscle fatigue is not explicitly listed as a common side effect of starting Lipitor (atorvastatin) [1]. According to the drug's official prescribing information, the most common side effects of Lipitor include diarrhea, upset stomach, and muscle pain [1]. However, it is essential to note that muscle-related side effects, including muscle pain, weakness, and cramping, have been reported in some patients taking Lipitor and other statins [1]. These muscle-related symptoms are typically mild; however, in rare cases, they can progress to a serious condition called rhabdomyolysis [1].

Patients should report any muscle symptoms to their healthcare provider promptly, as continuing the medication may be necessary or adjusting the dosage [1]. It is also important to note that muscle fatigue can have various causes, and it may not always be related to medication use [2].

In summary, while muscle fatigue is not explicitly listed as a common side effect of starting Lipitor, muscle-related symptoms have been reported in some patients taking the medication. Patients should consult their healthcare provider if they experience muscle symptoms while taking Lipitor.

Sources:

1. Lipitor (atorvastatin) [Prescribing Information]. Pfizer Labs. 2016. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020990s053,020991s049,021102s023lbl.pdf>
2. Muscle fatigue. Mayo Clinic. <https://www.mayoclinic.org/symptoms/muscle-fatigue/basics/causes/sym-20050913>
3. Statins. DrugPatentWatch.com. <https://www.drugpatentwatch.com/drugs/statins>