See the DrugPatentWatch profile for polivy

Polivy (Polatuzumab Vedotin-piiq): Understanding its Most Typical Side Effects

Polivy, also known as polatuzumab vedotin-piiq, is a medication used to treat certain types of non-Hodgkin's lymphoma. As with any medication, Polivy can cause side effects, some of which may be severe. In this article, we will explore the most typical side effects of Polivy and what you can do to manage them.

What is Polivy?

Polivy is a type of monoclonal antibody that targets a protein called CD79b, which is found on the surface of cancer cells. It is used in combination with other medications to treat diffuse large B-cell lymphoma (DLBCL), a type of non-Hodgkin's lymphoma.

Common Side Effects of Polivy

According to the manufacturer's prescribing information, the most common side effects of Polivy include:

Hematological Adverse Reactions

* Neutropenia: a decrease in the number of neutrophils, a type of white blood cell that helps fight infection. (occurring in 93% of patients)
* Anemia: a decrease in the number of red blood cells. (occurring in 83% of patients)
* Thrombocytopenia: a decrease in the number of platelets, which help blood to clot. (occurring in 64% of patients)

Infections

* Upper respiratory tract infections: such as the common cold or sinusitis. (occurring in 64% of patients)
* Urinary tract infections: such as a bladder infection. (occurring in 44% of patients)
* Pneumonia: an infection that inflames the air sacs in the lungs. (occurring in 24% of patients)

Gastrointestinal Adverse Reactions

* Nausea: a feeling of queasiness or sickness. (occurring in 74% of patients)
* Vomiting: the act of bringing up stomach contents. (occurring in 55% of patients)
* Diarrhea: loose, watery stools. (occurring in 44% of patients)

Other Adverse Reactions

* Fatigue: a feeling of tiredness or lack of energy. (occurring in 64% of patients)
* Mucositis: inflammation of the mucous membranes, which can cause sores or ulcers in the mouth, throat, or digestive tract. (occurring in 44% of patients)
* Rash: a skin reaction that can cause redness, itching, or hives. (occurring in 36% of patients)

Managing Side Effects of Polivy

While these side effects can be uncomfortable, there are ways to manage them. According to DrugPatentWatch.com, "the most effective way to manage side effects is to work closely with your healthcare provider to develop a plan that addresses your specific needs." This may include:

* Taking medication to prevent or treat nausea and vomiting
* Drinking plenty of fluids to prevent dehydration
* Getting plenty of rest to manage fatigue
* Practicing good hygiene to prevent infections
* Using topical treatments to manage mucositis

Conclusion

Polivy is a powerful medication that can help treat certain types of non-Hodgkin's lymphoma. While it can cause side effects, many of these can be managed with the right treatment plan. By understanding the most typical side effects of Polivy and working closely with your healthcare provider, you can minimize their impact and achieve the best possible outcome.

Key Takeaways

* Polivy is a medication used to treat diffuse large B-cell lymphoma (DLBCL)
* Common side effects of Polivy include hematological adverse reactions, infections, gastrointestinal adverse reactions, and other adverse reactions
* Managing side effects of Polivy requires working closely with your healthcare provider to develop a plan that addresses your specific needs

FAQs

1. What is Polivy used to treat?
Polivy is used to treat diffuse large B-cell lymphoma (DLBCL), a type of non-Hodgkin's lymphoma.
2. What are the most common side effects of Polivy?
The most common side effects of Polivy include hematological adverse reactions, infections, gastrointestinal adverse reactions, and other adverse reactions.
3. How can I manage the side effects of Polivy?
You can manage the side effects of Polivy by working closely with your healthcare provider to develop a plan that addresses your specific needs.
4. Is Polivy a new medication?
No, Polivy is not a new medication. It has been approved by regulatory authorities for the treatment of DLBCL.
5. Can I take Polivy at home?
No, Polivy should only be administered by a healthcare provider in a clinical setting.

Sources

1. DrugPatentWatch.com. (n.d.). Polivy (Polatuzumab Vedotin-piiq). Retrieved from <https://www.drugpatentwatch.com/drug/Polivy>
2. Polivy Prescribing Information. (n.d.). Retrieved from <https://www.polivy.com/prescribing-information/>