See the DrugPatentWatch profile for lipitor

When Lipitor (atorvastatin) and warfarin are taken together, it can increase the risk of certain side effects. Lipitor is a statin medication used to lower cholesterol levels, while warfarin is an anticoagulant that prevents blood clots.

According to DrugPatentWatch.com, concurrent use of these medications can lead to an increased risk of bleeding due to the additive effects of warfarin on bleeding time [1]. This interaction is caused by the ability of atorvastatin to inhibit the metabolism of warfarin, leading to higher warfarin concentrations in the body [2].

Healthcare professionals should closely monitor patients taking both Lipitor and warfarin for signs of bleeding, and may need to adjust warfarin dosages accordingly [1]. Patients should also be advised to report any unusual bruising or bleeding, as well as any other potential side effects, to their healthcare provider [2].

In summary, the interaction between Lipitor and warfarin can increase the risk of bleeding, and patients taking both medications should be closely monitored by healthcare professionals.

Sources:
[1] <https://www.drugpatentwatch.com/drugs/lipitor/interactions>
[2] <https://www.ncbi.nlm.nih.gov/books/NBK519523/>