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Grapefruit consumption may interact with the medication Lipitor, and it is recommended to exercise caution. This interaction can increase the concentration of Lipitor in the body, potentially leading to unwanted side effects [1]. The primary active ingredient in Lipitor is atorvastatin, a type of statin medication used to treat high cholesterol levels [2].

The United States Food and Drug Administration (FDA) advises patients to avoid consuming grapefruit or grapefruit juice while taking Lipitor [1]. This recommendation is due to a chemical found in grapefruits called furanocoumarins, which can interfere with the metabolism of Lipitor in the body [1].

The interaction between Lipitor and grapefruit can lead to an increased risk of side effects such as muscle pain and damage, liver damage, and kidney problems [1]. Patients should consult their healthcare provider or pharmacist for personalized advice regarding their medication and diet [1].

In summary, it is advisable to avoid consuming grapefruit or grapefruit juice while taking Lipitor due to the potential for increased drug concentration and potential side effects [1, 2].

Sources:
[1] U.S. Food & Drug Administration. (2022). Lipitor - atorvastatin calcium tablet. Retrieved from <https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/lipitor-atorvastatin-calcium-tablet>
[2] DrugPatentWatch. (2022). Lipitor (atorvastatin) Drug Patent Expiration & Generic Launch Dates. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>