See the DrugPatentWatch profile for lipitor

When considering the interaction between Lipitor (atorvastatin) and furosemide, it is important to be aware of the potential severe side effects. According to Drugs.com, a serious interaction can occur between these two medications, leading to an increased risk of certain adverse effects [1].

Lipitor is a statin medication used to lower cholesterol levels, while furosemide is a loop diuretic that helps the body eliminate excess fluid and sodium [1][2]. When used together, the risk of muscle damage (myopathy) and kidney problems may increase [1].

Muscle damage can manifest as muscle pain, weakness, or tenderness, and in severe cases, it can lead to rhabdomyolysis, a condition in which muscle tissue breaks down, releasing harmful substances into the bloodstream [1]. Symptoms of rhabdomyolysis include dark or cola-colored urine, fever, and muscle pain or weakness [1].

Kidney problems associated with the interaction between Lipitor and furosemide may include acute kidney injury or failure, which can be life-threatening if left untreated [1]. Symptoms of kidney problems include decreased urine output, swelling in the legs and ankles, and fatigue [1].

It is crucial to consult a healthcare provider before starting or stopping any medication, especially when considering the interaction between Lipitor and furosemide. Regular monitoring of kidney and muscle function may be necessary to ensure the safety and effectiveness of the treatment regimen [1].

Sources:
[1] <https://www.drugs.com/drug-interactions/atorvastatin-furosemide.html>
[2] <https://www.drugpatentwatch.com/drugs/lipitor>