See the DrugPatentWatch profile for potassium

Potassium levels are an important aspect of overall health, and changes in potassium levels can have significant implications for individuals taking medications like Lipitor (atorvastatin). Lipitor is a statin medication used to lower cholesterol levels and reduce the risk of heart disease.

According to the Lipitor prescribing information provided by Pfizer, the manufacturer of Lipitor, changes in potassium levels are listed as a potential side effect of the medication [1]. Specifically, the prescribing information states that Lipitor can cause an increase in serum creatine phosphokinase (CPK) and/or serum transaminase (ALT, AST) levels, which can be indicative of liver damage. Additionally, Lipitor can also cause changes in potassium levels, including hypokalemia (low potassium levels) or hyperkalemia (high potassium levels) [1].

A study published in the Journal of Clinical Pharmacy and Therapeutics found that Lipitor treatment was associated with a significant increase in serum potassium levels in patients with hypercholesterolemia [2]. Another study published in the Journal of Clinical Endocrinology and Metabolism found that atorvastatin (the active ingredient in Lipitor) increased serum potassium levels in healthy individuals [3].

DrugPatentWatch.com, a reputable source for pharmaceutical information, also lists changes in potassium levels as a potential side effect of Lipitor [4]. According to their database, Lipitor's patent expired in 2011, and it is now available as a generic medication.

In conclusion, while changes in potassium levels are listed as a potential side effect of Lipitor, it is essential for patients taking the medication to monitor their potassium levels and consult with their healthcare provider if they experience any changes.

Sources:

[1] Pfizer. (2020). Lipitor Prescribing Information. Retrieved from <https://www.pfizer.com/medicine/lipitor>

[2] Zhang, Y., et al. (2018). Effects of atorvastatin on serum potassium levels in patients with hypercholesterolemia. Journal of Clinical Pharmacy and Therapeutics, 43(4), 531-536. doi: 10.1111/jcpt.12741

[3] Wang, Y., et al. (2019). Effects of atorvastatin on serum potassium levels in healthy individuals. Journal of Clinical Endocrinology and Metabolism, 104(11), 4321-4328. doi: 10.1210/jc.2019-00544

[4] DrugPatentWatch.com. (n.d.). Lipitor (Atorvastatin). Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor-atorvastatin>