See the DrugPatentWatch profile for aspirin

Aspirin is a common medication used to treat pain, reduce inflammation, and prevent blood clots. However, it is also known to cause stomach-related side effects. When comparing aspirin's stomach-related side effects to other medications, it is essential to consider the type of aspirin and the dosage.

Aspirin can cause stomach irritation, ulcers, and bleeding, especially when taken in high doses or over an extended period. These side effects occur because aspirin inhibits the production of prostaglandins, which protect the stomach lining.

When comparing aspirin's stomach-related side effects to other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, aspirin may be less likely to cause stomach ulcers and bleeding [1]. However, this may not be the case for all individuals, and stomach-related side effects can still occur.

To reduce the risk of stomach-related side effects, enteric-coated aspirin was developed. This type of aspirin is designed to dissolve in the small intestine rather than the stomach, reducing the likelihood of stomach irritation. However, enteric-coated aspirin may not be as effective in preventing blood clots as regular aspirin [2].

It is important to note that stomach-related side effects can occur with any medication, and individual responses may vary. Factors such as age, overall health, and other medications being taken can affect an individual's risk of experiencing stomach-related side effects.

In summary, aspirin can cause stomach-related side effects, but its side effect profile may be more favorable compared to other NSAIDs. Enteric-coated aspirin may further reduce the risk of stomach irritation, but it may not be as effective in preventing blood clots.

Sources:

1. "NSAIDs and Stomach Ulcers." Mayo Clinic, Mayo Foundation for Medical Education and Research, 11 Jan. 2022, <https://www.mayoclinic.org/diseases-conditions/stomach-ulcers/in-depth/nsaids/art-20046563>.
2. "Enteric-Coated Aspirin." MedlinePlus, U.S. National Library of Medicine, 11 Jan. 2022, <https://medlineplus.gov/druginfo/meds/a682035.html>.
3. "Aspirin." DrugPatentWatch.com, <https://www.drugpatentwatch.com/drugs/aspirin>.