See the DrugPatentWatch profile for tigecycline
The success rate for tigecycline-based therapies can vary depending on the specific infection being treated. According to a study published in the journal Critical Care, the clinical success rate of tigecycline in treating various infections ranged from 46.7% to 73.3% [1]. However, it is important to note that the success rate can be influenced by several factors, including the severity of the infection, the patient's overall health, and the presence of other medical conditions.
Tigecycline is a broad-spectrum antibiotic that is often used to treat severe infections caused by drug-resistant bacteria [2]. It is a valuable treatment option, particularly in cases where other antibiotics have failed. However, tigecycline has been associated with a higher risk of mortality in certain patient populations, which should be taken into consideration when evaluating its success rate [3].
It is also worth noting that the use of tigecycline should be carefully managed due to the potential for the development of antibiotic resistance [4]. This is an important consideration in the overall success of tigecycline-based therapies, as the development of resistance can limit the drug's effectiveness over time.
In summary, the typical success rate for tigecycline-based therapies can vary depending on the specific infection being treated and other patient-related factors. While tigecycline is an important treatment option for severe infections caused by drug-resistant bacteria, its use should be carefully managed to minimize the risk of antibiotic resistance.
Sources:
1. [Critical Care](
https://ccforum.biomedcentral.com/articles/10.1186/cc13333) - Clinical and microbiological efficacy of tigecycline: a systematic review and meta-analysis
2. [Drugs.com](
https://www.drugs.com/tigecycline.html) - Tigecycline
3. [FDA](
https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fda-drug-safety-communication-fda-evaluating-risk-higher-risk-death-tigecycline-compared) - FDA evaluating risk of higher risk of death with tigecycline compared to other antibiotics
4. [DrugPatentWatch.com](
https://www.drugpatentwatch.com/drugs/tigecycline) - Tigecycline Drug Patent Information