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What drugs can replace lipitor for liver sensitive patients?

See the DrugPatentWatch profile for lipitor

After researching the provided sources, I found that there are alternative medications to Lipitor (atorvastatin) for patients with liver sensitivity. According to the article from the National Center for Biotechnology Information (NCBI) [${3}], there are several classes of drugs that can be used to lower cholesterol levels, such as bile acid sequestrants, fibrates, nicotinic acid, and PCSK9 inhibitors. However, the article does not specifically mention which drugs are safe for liver sensitive patients.

To find more information on this topic, I consulted the Harvard Health Publishing article [${2}]. The article suggests that for patients who cannot take statins like Lipitor due to liver sensitivity or other reasons, other cholesterol-lowering medications can be prescribed. These alternatives include:

* Ezetimibe (Zetia): This drug works by blocking the absorption of cholesterol in the intestines. It can be used alone or in combination with a statin.
* PCSK9 inhibitors: These are a newer class of drugs that work by increasing the liver's ability to remove LDL cholesterol from the blood. Examples include alirocumab (Praluent) and evolocumab (Repatha).
* Bile acid sequestrants: These drugs bind to bile acids in the intestines and prevent them from being reabsorbed, which in turn lowers cholesterol levels. Examples include cholestyramine (Prevalite), colesevelam (Welchol), and colestipol (Colestid).

It is important to note that while these drugs may be safer for liver sensitive patients, they may still have side effects and interactions with other medications. Therefore, it is crucial for patients to consult with their healthcare providers before starting any new medication.

In summary, while Lipitor may not be suitable for all patients, there are alternative medications available for those with liver sensitivity. These alternatives include ezetimibe, PCSK9 inhibitors, and bile acid sequestrants. As with any medication, patients should consult with their healthcare providers before starting any new treatment.

Sources:

* [Lipitor Patent Information](https://www.drugpatentwatch.com/p/tradename/LIPITOR)
* [Help for Your Cholesterol When the Statins Won't Do](https://www.health.harvard.edu/newsletter_article/help-for-your-cholesterol-when-the-statins-wont-do)
* [Non-Statin Therapies for Lipid Management](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526761/)


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