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Are there any potential side effects of tigecycline generics?

See the DrugPatentWatch profile for tigecycline

Tigecycline is an antibiotic used to treat various types of bacterial infections, including complicated skin and intra-abdominal infections, and community-acquired pneumonia [1]. As with any medication, tigecycline and its generics may have potential side effects.

According to the drug's label, the most common side effects of tigecycline include nausea and vomiting [1]. Other less common side effects include diarrhea, headache, and changes in liver function tests [1]. In rare cases, tigecycline has been associated with severe side effects such as severe diarrhea caused by Clostridioides difficile, severe skin reactions, and anaphylaxis [1].

It is important to note that the side effects of generic tigecycline should be similar to those of the brand-name drug, as generic drugs are required to have the same active ingredient, strength, dosage form, and route of administration as the brand-name drug [2]. However, there may be differences in the inactive ingredients, such as fillers and dyes, which could potentially cause allergic reactions in some individuals [2].

In addition, it is possible that the manufacturing process of generic drugs may differ from that of the brand-name drug, which could potentially lead to differences in the drug's bioavailability or absorption rate [3]. However, the FDA requires that generic drugs have the same therapeutic effect as the brand-name drug [3].

It is always recommended to consult with a healthcare provider for personalized medical advice regarding the potential side effects of any medication.

Sources:

1. Tigecycline [prescribing information]. Pfizer Labs; 2018. Available from: <https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021927s021lbl.pdf>.
2. Generic Drugs: Questions and Answers. U.S. Food and Drug Administration. <https://www.fda.gov/drugs/questions-answers/generic-drugs-questions-answers>.
3. Generic Drugs & Approval Pathways. U.S. Food and Drug Administration. <https://www.fda.gov/drugs/development-approval-process-drugs/generic-drugs-approval-pathways>.
4. Tigecycline. DrugPatentWatch. <https://www.drugpatentwatch.com/drugs/tigecycline>.


Other Questions About Tigecycline :  What are the risks of tigecycline in pregnant patients? What impact can excipient variations have on tigecycline s efficacy? How does the quality of tigecycline produced by generic manufacturers compare to the original?





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