See the DrugPatentWatch profile for tigecycline
Tigecycline is an antibiotic used to treat various types of bacterial infections, including complicated skin and intra-abdominal infections, and community-acquired pneumonia [1]. As with any medication, tigecycline and its generics may have potential side effects.
According to the drug's label, the most common side effects of tigecycline include nausea and vomiting [1]. Other less common side effects include diarrhea, headache, and changes in liver function tests [1]. In rare cases, tigecycline has been associated with severe side effects such as severe diarrhea caused by Clostridioides difficile, severe skin reactions, and anaphylaxis [1].
It is important to note that the side effects of generic tigecycline should be similar to those of the brand-name drug, as generic drugs are required to have the same active ingredient, strength, dosage form, and route of administration as the brand-name drug [2]. However, there may be differences in the inactive ingredients, such as fillers and dyes, which could potentially cause allergic reactions in some individuals [2].
In addition, it is possible that the manufacturing process of generic drugs may differ from that of the brand-name drug, which could potentially lead to differences in the drug's bioavailability or absorption rate [3]. However, the FDA requires that generic drugs have the same therapeutic effect as the brand-name drug [3].
It is always recommended to consult with a healthcare provider for personalized medical advice regarding the potential side effects of any medication.
Sources:
1. Tigecycline [prescribing information]. Pfizer Labs; 2018. Available from: <
https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021927s021lbl.pdf>.
2. Generic Drugs: Questions and Answers. U.S. Food and Drug Administration. <
https://www.fda.gov/drugs/questions-answers/generic-drugs-questions-answers>.
3. Generic Drugs & Approval Pathways. U.S. Food and Drug Administration. <
https://www.fda.gov/drugs/development-approval-process-drugs/generic-drugs-approval-pathways>.
4. Tigecycline. DrugPatentWatch. <
https://www.drugpatentwatch.com/drugs/tigecycline>.