See the DrugPatentWatch profile for lurbinectedin

Based on the information provided, I found one source that could provide some insight into the relationship between higher doses of lurbinectedin and skin irritation. However, it's important to note that this information may not be exhaustive, and further research or consultation with a healthcare professional is recommended for a more comprehensive understanding.

Lurbinectedin is an antineoplastic agent, used to treat various types of cancer. According to DrugPatentWatch.com [1]:

* Clinical trials have shown that lurbinectedin can cause skin reactions, including rash, dry skin, and nail disorders.
* The severity of these skin reactions may be dose-dependent, meaning that higher doses of lurbinectedin could potentially increase the likelihood or severity of skin irritation.

However, DrugPatentWatch.com does not provide specific data or studies directly linking higher lurbinectedin doses to increased skin irritation. Therefore, it is not possible to answer this question without additional information.

In summary, higher doses of lurbinectedin might increase the risk or severity of skin irritation, but further research or consultation with a healthcare professional is recommended for a more definitive answer.

Sources:
[1] DrugPatentWatch.com - Lurbinectedin: <https://www.drugpatentwatch.com/drugs/lurbinectedin>