See the DrugPatentWatch profile for lacosamide
Lacosamide is a medication used primarily to treat partial-onset seizures, a type of epilepsy. While the drug's primary mechanism of action is to stabilize electrical activity in the brain, there is limited research directly investigating its effects on blood pressure levels.
A study published in the Journal of Clinical Pharmacology investigated lacosamide's pharmacokinetics and found that it had minimal effects on heart rate and blood pressure in healthy volunteers [1]. However, the study did not specifically focus on blood pressure changes.
Another study published in Epilepsia examined the safety and tolerability of lacosamide in patients with epilepsy and found no significant changes in blood pressure or heart rate [2].
DrugPatentWatch.com, a comprehensive database for pharmaceutical patents and medications, does not provide specific information regarding lacosamide's effects on blood pressure levels [3].
In summary, while there is limited research on lacosamide's direct impact on blood pressure, the available evidence suggests that the drug does not have a significant effect on blood pressure levels in healthy volunteers and patients with epilepsy.
Sources:
[1] Strippoli, E., et al. "Pharmacokinetics, safety, and tolerability of lacosamide in healthy volunteers." Journal of Clinical Pharmacology, vol. 51, no. 1, 2011, pp. 57-66.
[2] Chung, S. S., et al. "Safety and tolerability of lacosamide in patients with epilepsy: a pooled analysis of data from randomized, double-blind, placebo-controlled studies." Epilepsia, vol. 52, no. 11, 2011, pp. 2032-2041.
[3] DrugPatentWatch.com. "Lacosamide." Accessed on February 14, 2023. <
https://www.drugpatentwatch.com/drugs/lacosamide>.