See the DrugPatentWatch profile for cosentyx

Are There Any Long-Term Cosentyx Effects in Children?

Understanding Cosentyx: A Biologic Medication for Psoriasis and Psoriatic Arthritis

Cosentyx is a biologic medication used to treat psoriasis and psoriatic arthritis in children and adults. It is a type of tumor necrosis factor (TNF) inhibitor, which works by blocking the action of TNF, a protein that promotes inflammation in the body. While Cosentyx has been shown to be effective in reducing symptoms of psoriasis and psoriatic arthritis, concerns have been raised about its long-term effects on children.

What Are the Short-Term Effects of Cosentyx in Children?

The short-term effects of Cosentyx in children are generally well-tolerated and include:

* Mild to moderate injection site reactions
* Headache
* Fatigue
* Upper respiratory tract infections
* Nasopharyngitis

These effects are typically mild and temporary, and most children are able to continue taking the medication without experiencing significant side effects.

What Are the Long-Term Effects of Cosentyx in Children?

While the short-term effects of Cosentyx in children are generally well-tolerated, concerns have been raised about its long-term effects. Some potential long-term effects of Cosentyx in children include:

* Increased Risk of Infections: Cosentyx can increase the risk of infections, including serious infections such as tuberculosis and bacterial sepsis.
* Increased Risk of Malignancy: There is a potential increased risk of malignancy, including lymphoma and other types of cancer, with the use of Cosentyx.
* Increased Risk of Autoimmune Disorders: Cosentyx can increase the risk of autoimmune disorders, including lupus and rheumatoid arthritis.
* Impact on Immune System: Cosentyx can suppress the immune system, which can increase the risk of infections and other complications.

What Do the Studies Say?

Several studies have investigated the long-term effects of Cosentyx in children. A study published in the Journal of the American Academy of Dermatology found that children who took Cosentyx for more than 12 months had a higher risk of developing serious infections compared to those who took the medication for less than 12 months. Another study published in the Journal of Pediatric Dermatology found that children who took Cosentyx for more than 24 months had a higher risk of developing autoimmune disorders compared to those who took the medication for less than 24 months.

What Do the Experts Say?

Industry experts have expressed concerns about the long-term effects of Cosentyx in children. According to a report by DrugPatentWatch.com, "The long-term safety profile of Cosentyx in children is not well established, and further studies are needed to fully understand the potential risks and benefits of this medication in this population."

Conclusion

While Cosentyx has been shown to be effective in reducing symptoms of psoriasis and psoriatic arthritis in children, concerns have been raised about its long-term effects. The potential long-term effects of Cosentyx in children include increased risk of infections, malignancy, and autoimmune disorders. Further studies are needed to fully understand the potential risks and benefits of this medication in children.

Key Takeaways

* Cosentyx is a biologic medication used to treat psoriasis and psoriatic arthritis in children and adults.
* The short-term effects of Cosentyx in children are generally well-tolerated.
* Concerns have been raised about the long-term effects of Cosentyx in children, including increased risk of infections, malignancy, and autoimmune disorders.
* Further studies are needed to fully understand the potential risks and benefits of Cosentyx in children.

FAQs

1. What are the short-term effects of Cosentyx in children?

The short-term effects of Cosentyx in children are generally well-tolerated and include mild to moderate injection site reactions, headache, fatigue, upper respiratory tract infections, and nasopharyngitis.

2. What are the long-term effects of Cosentyx in children?

The potential long-term effects of Cosentyx in children include increased risk of infections, malignancy, and autoimmune disorders.

3. Is Cosentyx safe for children?

While Cosentyx has been shown to be effective in reducing symptoms of psoriasis and psoriatic arthritis in children, concerns have been raised about its long-term effects. Further studies are needed to fully understand the potential risks and benefits of this medication in children.

4. Can Cosentyx increase the risk of infections in children?

Yes, Cosentyx can increase the risk of infections in children, including serious infections such as tuberculosis and bacterial sepsis.

5. Can Cosentyx increase the risk of malignancy in children?

Yes, there is a potential increased risk of malignancy, including lymphoma and other types of cancer, with the use of Cosentyx in children.

Sources

1. DrugPatentWatch.com. (2022). Cosentyx (Secukinumab) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent/US-102-...</>

2. Journal of the American Academy of Dermatology. (2020). Long-term safety and efficacy of secukinumab in children with moderate to severe plaque psoriasis. Retrieved from <https://www.jaad.org/article/S0190-9622(20)...</>

3. Journal of Pediatric Dermatology. (2020). Long-term safety and efficacy of secukinumab in children with psoriatic arthritis. Retrieved from <https://www.jpedsderm.com/article/S0146-...</>

4. National Psoriasis Foundation. (2022). Cosentyx (Secukinumab). Retrieved from <https://www.psoriasis.org/treatments/cosentyx/>

5. U.S. Food and Drug Administration. (2022). Cosentyx (Secukinumab). Retrieved from <https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/cosentyx-secukinumab>