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The Age Range of Polivy: Understanding the Clinical Trials

Polivy, also known as polatuzumab vedotin-piiq, is a medication used to treat certain types of non-Hodgkin's lymphoma. As a relatively new medication, it's essential to understand the age range of patients who have participated in clinical trials to assess its safety and efficacy. In this article, we'll delve into the age range of patients who have participated in Polivy's clinical trials and explore the implications for its use in different age groups.

Clinical Trials: The Foundation of Polivy's Development

Before we dive into the age range of patients in Polivy's clinical trials, it's essential to understand the importance of clinical trials in the development of new medications. Clinical trials are designed to assess the safety and efficacy of a medication in a controlled environment, involving human participants. These trials provide valuable insights into a medication's potential benefits and risks, which are crucial for regulatory approval and subsequent use in clinical practice.

Age Range of Patients in Polivy's Clinical Trials

According to the clinical trial data available on DrugPatentWatch.com, the age range of patients who have participated in Polivy's clinical trials is quite broad. In the pivotal clinical trial, known as the POLARIS trial, patients ranged in age from 18 to 85 years old. This wide age range is not uncommon in clinical trials, as it allows researchers to assess a medication's safety and efficacy across different age groups.

Younger Patients: The Focus on Relapsed or Refractory DLBCL

In the POLARIS trial, the majority of patients were diagnosed with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), a type of non-Hodgkin's lymphoma. These patients were typically younger, with a median age of 63 years old. The inclusion of younger patients in clinical trials is crucial, as it allows researchers to assess the medication's safety and efficacy in this age group.

Older Patients: The Importance of Geriatric Considerations

While the majority of patients in the POLARIS trial were younger, older patients were also included. In fact, 15% of patients were 75 years old or older. This is significant, as older patients often have unique health considerations that can impact the safety and efficacy of a medication. The inclusion of older patients in clinical trials is essential for ensuring that medications are safe and effective for all age groups.

Geriatric Considerations: A Growing Concern

As the global population ages, geriatric considerations are becoming increasingly important in clinical trials. Older patients often have comorbidities, take multiple medications, and may have decreased organ function, which can impact the safety and efficacy of a medication. The inclusion of older patients in clinical trials helps researchers to better understand these complexities and develop medications that are safe and effective for this age group.

Conclusion

In conclusion, the age range of patients in Polivy's clinical trials is quite broad, ranging from 18 to 85 years old. The inclusion of patients across different age groups is essential for assessing a medication's safety and efficacy. While younger patients were the focus of the POLARIS trial, older patients were also included, highlighting the importance of geriatric considerations in clinical trials.

Frequently Asked Questions

1. What is the age range of patients in Polivy's clinical trials?

The age range of patients in Polivy's clinical trials is 18 to 85 years old.

2. What is the focus of Polivy's clinical trials?

The focus of Polivy's clinical trials is on treating relapsed or refractory diffuse large B-cell lymphoma (DLBCL).

3. Why is it important to include older patients in clinical trials?

It's essential to include older patients in clinical trials to ensure that medications are safe and effective for this age group, which is often impacted by comorbidities and decreased organ function.

4. What is the significance of the POLARIS trial?

The POLARIS trial is significant because it assessed the safety and efficacy of Polivy in patients with relapsed or refractory DLBCL, including older patients.

5. What is the importance of geriatric considerations in clinical trials?

Geriatric considerations are essential in clinical trials because older patients often have unique health considerations that can impact the safety and efficacy of a medication.

Sources

1. DrugPatentWatch.com. (n.d.). Polatuzumab Vedotin-Piiq (Polivy). Retrieved from <https://www.drugpatentwatch.com/drug/palatuzumab-vedotin-piiq-polivy/>

Highlight

"The inclusion of older patients in clinical trials is essential for ensuring that medications are safe and effective for all age groups." - Geriatric Considerations: A Growing Concern

Note: The highlight is a quote from the article, and the citation is to the original source, which is the article itself.