See the DrugPatentWatch profile for lyrica

Lyrica, also known as pregabalin, is a medication used to treat various conditions such as epilepsy, anxiety, and pain neuropathy [1]. There is currently no scientific evidence to suggest that Lyrica directly interacts with alcohol to worsen hangovers. However, both Lyrica and alcohol can cause drowsiness, dizziness, and impaired coordination [2][3]. Therefore, combining the two substances may increase the risk and severity of these side effects.

It is important to note that mixing any medication with alcohol can have unpredictable effects and may increase the risk of adverse reactions. It is always recommended to consult with a healthcare provider or pharmacist before mixing medication with alcohol [4].

In summary, while there is no direct evidence that Lyrica interacts with alcohol to worsen hangovers, both substances can cause similar side effects, and combining them may increase the risk and severity of these side effects.

Sources:

1. "Pregabalin (Lyrica)" [Drugs.com] <https://www.drugs.com/pregabalin.html>
2. "Pregabalin (Oral Route) Side Effects" [Mayo Clinic] <https://www.mayoclinic.org/drugs-supplements/pregabalin-oral-route/side-effects/drg-20063395>
3. "Alcohol" [NIDA] <https://www.drugabuse.gov/drug-topics/alcohol>
4. "Mixing Alcohol with Medicines" [NIH] <https://medlineplus.gov/ency/article/002628.htm>