See the DrugPatentWatch profile for tigecycline
Based on the information available, there is a lack of direct comparison between generic and branded Tigecycline in clinical trials. However, Tigecycline, regardless of being generic or branded, is a widely used antibiotic that has been proven effective against a variety of bacterial infections.
Tigecycline, a broad-spectrum antibiotic, is used to treat various infections caused by susceptible bacteria, including complicated skin and skin structure infections, complicated intra-abdominal infections, and community-acquired bacterial pneumonia [1]. The branded version of Tigecycline is Tygacil, which was approved by the FDA in 2005 [2].
Generic drugs are equivalent to their brand-name counterparts in dosage, safety, strength, quality, the way they work, the way they are taken, and the way they should be used [3]. Therefore, generic Tigecycline is expected to have the same effectiveness as the branded one.
However, it is important to note that the effectiveness of Tigecycline can vary depending on the specific bacterial infection being treated, the patient's overall health, and the patient's compliance with the prescribed treatment regimen [1].
In conclusion, while there is a lack of direct comparison between generic and branded Tigecycline in clinical trials, generic Tigecycline is expected to have the same effectiveness as the branded one due to the equivalence in dosage, safety, strength, quality, and the way they work.
Sources:
[1] Tigecycline. (2019). In Mayo Clinic Diseases and Conditions. Retrieved from
https://www.mayoclinic.org/drugs-supplements/tigecycline-oral-route/description/drg-20066534
[2] Tygacil. (2019). In Drugs.com. Retrieved from
https://www.drugs.com/tygacil.html
[3] Generic Drugs: Questions and Answers. (2019). In FDA. Retrieved from
https://www.fda.gov/drugs/understanding-generic-drugs/generic-drugs-questions-and-answers
Additional source for DrugPatentWatch.com:
[4] DrugPatentWatch. (2021). Tigecycline. Retrieved from
https://www.drugpatentwatch.com/drugs/tigecycline