See the DrugPatentWatch profile for keytruda

Keytruda, also known as pembrolizumab, is a type of immunotherapy medication used to treat various types of cancer. While Keytruda has been shown to be effective in treating cancer, it can also cause side effects. The frequency and severity of these side effects can change over time with long-term use.

According to DrugPatentWatch.com, Keytruda can cause a variety of side effects, including fatigue, cough, nausea, itching, rash, and joint pain [1]. Some side effects, such as fatigue and joint pain, may become more frequent or severe over time with long-term use. Additionally, Keytruda can cause serious side effects, such as immune-mediated side effects and infusion reactions, which can occur at any time during treatment [1].

Immune-mediated side effects occur when Keytruda affects the normal functioning of the immune system, leading to inflammation and damage in various organs and tissues [1]. These side effects can affect any organ or system in the body and can occur at any time during treatment [1]. Some immune-mediated side effects, such as pneumonitis and colitis, may become more frequent or severe over time with long-term use [1].

Infusion reactions are another serious side effect of Keytruda that can occur at any time during treatment [1]. These reactions can cause symptoms such as fever, chills, weakness, and difficulty breathing [1]. While infusion reactions are more common during the first few infusions of Keytruda, they can also occur with long-term use [1].

It is important for patients to report any new or worsening side effects to their healthcare provider as soon as possible [1]. Healthcare providers may need to adjust the dose of Keytruda or provide additional treatments to manage side effects [1].

In summary, Keytruda can cause a variety of side effects, some of which may become more frequent or severe over time with long-term use. Immune-mediated side effects and infusion reactions are serious side effects that can occur at any time during treatment. Patients should report any new or worsening side effects to their healthcare provider as soon as possible.

Sources:

1. DrugPatentWatch.com. (n.d.). Keytruda (pembrolizumab) side effects by duration. Retrieved from <https://www.drugpatentwatch.com/drugs/keytruda/side-effects/duration>.