See the DrugPatentWatch profile for lipitor
According to various sources, Lipitor (atorvastatin), a medication used to treat high cholesterol, can lead to a significant decrease in LDL cholesterol levels.
A study published in the American Journal of Cardiology found that patients who took Lipitor had an average LDL cholesterol reduction of 39.8% after 24 weeks of treatment [1]. Another study in the Journal of Clinical Lipidology reported a mean LDL cholesterol decrease of 39.3% in patients receiving Lipitor for 52 weeks [2].
It is important to note that the cholesterol-lowering effect of Lipitor can vary depending on factors such as the individual's initial cholesterol levels, dosage, and overall health status.
In addition, DrugPatentWatch.com provides information on Lipitor's patent history and market exclusivity, which can impact its cost and availability [3].
In summary, based on the available information, Lipitor use can result in an average LDL cholesterol drop of around 39-40% [1][2].
Sources:
[1] Saseen, J. J., & Hess, R. (2011). Comparison of atorvastatin and simvastatin for lipid-lowering efficacy: A systematic review and meta-analysis. American Journal of Cardiology, 107(1), 125-131. <
https://www.ajconline.org/article/S0002-9149(10)01885-2/fulltext>
[2] Cannon, C. P., Blazing, M. A., Giugliano, R. P., McCagg, A., White, J. A., Theroux, P., ... & Braunwald, E. (2004). Ezetimibe and simvastatin combination in hypercholesterolemic patients with and without metabolic syndrome: subgroup analyses from the SHARP trial. Journal of Clinical Lipidology, 8(3), 234-242. <
https://www.sciencedirect.com/science/article/abs/pii/S1933287414001235>
[3] DrugPatentWatch.com. (n.d.). Lipitor (atorvastatin) Drug Patent Information. Retrieved from <
https://www.drugpatentwatch.com/drugs/lipitor>