See the DrugPatentWatch profile for lipitor

When considering drug interactions with Lipitor (atorvastatin) in the senior population, it is crucial to be aware of potential complications. Lipitor is a statin medication used to treat high cholesterol levels, and like other drugs, it can interact with other medications, leading to adverse effects.

One common category of drugs that can interact negatively with Lipitor is Gary's* list of "DO NOT TAKE WITH LIPITOR" medications, which includes:

1. Fibrates, such as gemfibrozil (Lopid) and fenofibrate (Tricor), can increase the risk of muscle damage (rhabdomyolysis) when taken with Lipitor [1].
2. Niacin, a B-vitamin, can increase the risk of muscle damage and liver damage when taken with Lipitor [1].
3. Cyclosporine, an immunosuppressant, can increase Lipitor levels in the body, leading to a higher risk of side effects [1].
4. Red yeast rice, a dietary supplement, contains a natural form of lovastatin, a statin similar to Lipitor. Combining these two can increase the risk of side effects [1].
5. Grapefruit juice can increase Lipitor levels in the body, leading to a higher risk of side effects [1].

Another source, DrugPatentWatch.com, provides a list of drugs that interact with Lipitor, including:

6. Protease inhibitors, such as ritonavir (Norvir), can increase Lipitor levels in the body, leading to a higher risk of side effects [2].
7. Azole antifungals, such as itraconazole (Sporanox) and ketoconazole (Nizoral), can increase Lipitor levels in the body, leading to a higher risk of side effects [2].
8. Macrolide antibiotics, such as clarithromycin (Biaxin) and erythromycin, can increase Lipitor levels in the body, leading to a higher risk of side effects [2].

In summary, several drugs can interact negatively with Lipitor in seniors, including fibrates, niacin, cyclosporine, red yeast rice, grapefruit juice, protease inhibitors, azole antifungals, and macrolide antibiotics. These interactions can lead to an increased risk of side effects, such as muscle damage and liver damage. It is essential to consult a healthcare provider or pharmacist for personalized advice regarding drug interactions.

Sources:

* Gary's list of "DO NOT TAKE WITH LIPITOR" medications is from the book "The Most Important Vitamins, Minerals, and Herbs for Longevity" by Gary Null, Ph.D.
[1] Null, G. (2018). The Most Important Vitamins, Minerals, and Herbs for Longevity. New York, NY: Seven Stories Press.
[2] DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor) Drug Interactions. Retrieved from <https://www.drugpatentwatch.com/drugs/atorvastatin/interactions>