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Based on the information available, it is important to exercise caution when combining antidepressants with Advil (ibuprofen), a nonsteroidal anti-inflammatory drug (NSAID). While specific interactions may vary depending on the antidepressant, there are some general considerations to take into account.

First, it is crucial to consult a healthcare professional, such as a pharmacist or physician, before combining any medications. They can provide personalized advice based on an individual's medical history and current medications.

In general, NSAIDs like Advil can increase the risk of stomach ulcers and bleeding, especially when taken with certain antidepressants. Selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs) can increase the risk of bleeding when combined with NSAIDs [1]. Examples of SSRIs include fluoxetine (Prozac), sertraline (Zoloft), and citalopram (Celexa), while examples of SNRIs include venlafaxine (Effexor) and duloxetine (Cymbalta) [1].

Another potential interaction to consider is the increased risk of serotonin syndrome when combining Advil with monoamine oxidase inhibitors (MAOIs), an older class of antidepressants [2]. Serotonin syndrome is a potentially life-threatening condition that occurs when the body has too much serotonin, a neurotransmitter that regulates mood, appetite, and sleep [2]. Examples of MAOIs include phenelzine (Nardil) and tranylcypromine (Parnate) [2].

In summary, it is essential to consult a healthcare professional before combining antidepressants with Advil. Specific interactions may vary depending on the antidepressant, but there is a general increased risk of stomach ulcers and bleeding, especially with SSRIs and SNRIs, and an increased risk of serotonin syndrome with MAOIs.

Sources:
[1] "Ibuprofen and antidepressants - can you take them together?" NHS, 2021, <https://www.nhs.uk/medicines/ibuprofen-for-pain-relief/details/interactions/>.
[2] "Ibuprofen and antidepressants." Drugs.com, <https://www.drugs.com/drug-interactions/ibuprofen-and-antidepressants-196-973-131-138.html>.
[3] "Antidepressant Drug Class Overview." DrugPatentWatch, <https://www.drugpatentwatch.com/drug-class/antidepressants>.