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When combining Lipitor, a cholesterol-lowering drug, with blood pressure medication, it is generally recommended to adjust the dosage under the supervision of a healthcare professional. This is due to the potential for drug interactions, which can increase the risk of side effects or reduce the effectiveness of one or both medications [1].

Lipitor, also known as atorvastatin, works by blocking an enzyme in the body that is needed to make cholesterol [2]. Blood pressure medications, on the other hand, work in various ways to lower blood pressure, such as relaxing blood vessels or reducing the amount of fluid in the body [3].

When combining these two types of medications, it is important to consider the potential for interactions. For example, Lipitor can increase the blood-pressure-lowering effects of certain blood pressure medications, which can lead to low blood pressure and dizziness [1]. Additionally, Lipitor can increase the risk of muscle damage when combined with certain blood pressure medications, such as calcium channel blockers [1].

Therefore, it is crucial to consult with a healthcare professional before adjusting the dosage of any medication, including Lipitor and blood pressure medications. A healthcare professional can evaluate the potential for drug interactions, consider the individual's medical history and current medications, and make any necessary dosage adjustments [1].

In summary, when combining Lipitor with blood pressure medication, it is recommended to adjust the dosage under the supervision of a healthcare professional due to the potential for drug interactions.

Sources:

1. "Atorvastatin." MedlinePlus, U.S. National Library of Medicine, 11 Jan. 2022, <https://medlineplus.gov/druginfo/meds/a601245.html>.
2. "Atorvastatin (Oral Route) Description and Brand Names." Mayo Clinic, Mayo Foundation for Medical Education and Research, 1 Jan. 2022, <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20063007>.
3. "Blood Pressure Medications." Mayo Clinic, Mayo Foundation for Medical Education and Research, 1 Jan. 2022, <https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/blood-pressure-medications/art-20046989>.
4. "Lipitor." DrugPatentWatch, <https://www.drugpatentwatch.com/drugs/lipitor>.