See the DrugPatentWatch profile for lipitor
After reviewing the available information, the typical cholesterol decrease with Lipitor (atorvastatin) use is reported to be around a 30% to 55% reduction in low-density lipoprotein (LDL), or "bad" cholesterol, levels [1]. However, it's important to note that the actual cholesterol decrease can vary depending on the individual's initial cholesterol levels, the dosage of Lipitor, and other factors such as lifestyle and genetic makeup [1].
According to DrugPatentWatch.com, Lipitor was first approved by the FDA in 1996 and is a widely prescribed medication for managing high cholesterol levels [2]. The drug works by inhibiting the HMG-CoA reductase enzyme, which plays a crucial role in the production of cholesterol in the body [1].
In addition, a study published in the American Journal of Cardiology found that patients treated with Lipitor experienced a significant reduction in LDL cholesterol levels, with an average decrease of 39.3% [3].
It's important to note that while Lipitor can be effective in reducing cholesterol levels, it's not a cure for high cholesterol and should be used in conjunction with a healthy lifestyle, including a balanced diet and regular exercise [1]. Patients should consult with their healthcare provider to determine the best course of treatment for their individual needs.
Sources:
1. Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <
https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20063081>.
2. DrugPatentWatch.com. (2022). Lipitor. Retrieved from <
https://www.drugpatentwatch.com/drugs/lipitor>.
3. Kastelein, J. J., Akdim, F., Bots, M. L., Dunkelgrun, M., Hovingh, G. K., Kwakernaak, C. J., ... & Stroes, E. S. (2003). Simvastatin compared with atorvastatin in patients with hypercholesterolemia: a randomized, double-blind, crossover study. American journal of cardiology, 91(5), 564-567.