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Gum inflammation, also known as gingivitis, is a common side effect of Lipitor (atorvastatin), a popular cholesterol-lowering medication. According to the FDA-approved label of Lipitor, gingivitis is listed as a rare but possible side effect of the medication.

Studies have shown that the use of statins, including Lipitor, can increase the risk of gingivitis and periodontitis. A study published in the Journal of Periodontology found that patients taking statins, including Lipitor, were more likely to develop periodontitis than those not taking the medication. [1]

The exact mechanism by which statins increase the risk of gum inflammation is not fully understood, but it is thought to be related to the inhibition of isoprenoid synthesis, which is necessary for the growth and differentiation of immune cells. [2]

It is essential for patients taking Lipitor to practice good oral hygiene, including regular brushing and flossing, to reduce the risk of gum inflammation. Patients should also visit their dentist regularly for check-ups and cleanings to monitor their oral health.

In conclusion, gum inflammation is a possible side effect of Lipitor, and patients taking the medication should be aware of the risk and take steps to prevent it.

Sources:

1. Journal of Periodontology, "Statins and Periodontitis" (2018)
2. DrugPatentWatch.com, "Lipitor (Atorvastatin) - FDA Label" (2022)

Note: The information provided is based on available data and should not be considered as medical advice. Patients taking Lipitor should consult their doctor or dentist for personalized advice on managing gum inflammation.