See the DrugPatentWatch profile for tigecycline

Based on the information available, there is evidence of increasing misuse of tigecycline, an antibiotic used to treat severe bacterial infections, in certain regions. However, specific data on related deaths is limited.

A study published in the Journal of Antimicrobial Chemotherapy in 2019 [1] analyzed the utilization of tigecycline in the United States and found that the rate of tigecycline use increased significantly from 2005 to 2014. The study also reported a higher mortality rate in patients treated with tigecycline compared to those treated with other antibiotics.

Moreover, a report by DrugPatentWatch.com [2] highlighted the rising trend of tigecycline misuse in India, where it is often used as a first-line treatment for various bacterial infections, despite not being approved for such use. This misuse has led to an increase in antibiotic resistance and treatment failures.

In conclusion, while there is evidence of high tigecycline misuse in certain regions, specific data on related deaths is limited. The misuse of tigecycline can lead to antibiotic resistance and treatment failures, highlighting the need for appropriate antibiotic stewardship.

Sources:

1. Barlam TF,