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Yes, elderly individuals may be more susceptible to drug interactions related to Lipitor (atorvastatin). As people age, they often experience physiological changes that can affect the way their bodies process and respond to medications [1].

Lipitor, a statin medication used to lower cholesterol levels, can interact with various other drugs, potentially leading to adverse effects [2]. Some factors that may increase the risk of these interactions in the elderly include:

1. Polypharmacy: Older adults often take multiple medications, which increases the likelihood of drug-drug interactions [1].
2. Decreased renal and hepatic function: Age-related declines in kidney and liver function can affect the metabolism and elimination of drugs, including Lipitor [1].
3. Changes in body composition: Age-related changes in body composition, such as increased body fat and decreased muscle mass, can affect drug distribution and clearance [1].

It is essential for healthcare providers to closely monitor elderly patients taking Lipitor, especially when other medications are involved. Regular evaluations of medication regimens, dosages, and potential interactions can help minimize the risks associated with Lipitor use in the elderly [1].

Sources:
[1] US National Library of Medicine. (2021). Geriatric Drug Therapy. In: Older People With Multimorbidity. <https://www.ncbi.nlm.nih.gov/books/NBK221732/>
[2] Drugs.com. (2021). Lipitor Interactions. <https://www.drugs.com/drug-interactions/atorvastatin,lipitor.html>
[3] DrugPatentWatch.com. (2021). Atorvastatin (Lipitor). <https://www.drugpatentwatch.com/drugs/atorvastatin>