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While Lipitor, a medication used to treat high cholesterol, has been extensively studied, there is limited research available on the interaction of Lipitor with other citrus fruits beyond grapefruit [1].
Grapefruit is known to interact with Lipitor and other statins, a group of cholesterol-lowering medications, due to a compound in grapefruit that can interfere with the body's metabolism of the drug [1]. This interaction can lead to increased levels of the drug in the body, which can increase the risk of side effects [1].
However, there is no substantial evidence to suggest that other citrus fruits, such as oranges, tangerines, or lemons, have a similar interaction with Lipitor [1]. In fact, a study published in the Journal of Agricultural and Food Chemistry found that compounds in oranges and tangerines do not have the same effect on drug metabolism as those in grapefruit [2].
It is always important to consult with a healthcare provider or pharmacist before consuming large amounts of citrus fruits or their juices while taking Lipitor or any other medication, as individual reactions can vary [1].
In conclusion, while grapefruit is known to interact with Lipitor, there is no significant evidence to suggest that other citrus fruits have the same effect.
Sources:
[1] DrugPatentWatch.com, "Grapefruit Juice and Statins: An Interaction You Should Know About," <
https://www.drugpatentwatch.com/blog/grapefruit-juice-and-statins-an-interaction-you-should-know-about/>
[2] Journal of Agricultural and Food Chemistry, "Comparison of the Effects of Orange, Grapefruit, and Tangerine Juices on the Pharmacokinetics of Felodipine in Humans," <
https://pubs.acs.org/doi/abs/10.1021/jf034943k>