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Ibuprofen, the active ingredient in Advil, is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of certain chemicals in the body called prostaglandins [1]. Prostaglandins are produced in response to injury or inflammation, and they cause pain and inflammation. By blocking the production of prostaglandins, ibuprofen helps to reduce pain and inflammation.
Ibuprofen works by inhibiting the activity of cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins. There are two main types of COX enzymes: COX-1 and COX-2. COX-1 is produced continuously in the body and is involved in maintaining the lining of the stomach and the regulation of blood flow to the kidneys. COX-2, on the other hand, is produced in response to injury or inflammation. Ibuprofen inhibits both COX-1 and COX-2, which is why it is effective at reducing pain and inflammation [2].
It is important to note that while ibuprofen can provide rapid relief from pain and inflammation, it can also have side effects, particularly if it is taken in large doses or for long periods of time. Some of the potential side effects of ibuprofen include stomach ulcers, stomach bleeding, and kidney damage [3].
In summary, the active ingredient in Advil, ibuprofen, works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. Ibuprofen inhibits the activity of COX enzymes, which are involved in the production of prostaglandins. While ibuprofen can provide rapid relief from pain and inflammation, it can also have side effects, particularly if it is taken in large doses or for long periods of time.
Sources:
1. "Ibuprofen." MedlinePlus, U.S. National Library of Medicine, 1 Sept. 2020, medlineplus.gov/druginfo/meds/a682035.html.
2. "Ibuprofen: MedlinePlus Drug Information." MedlinePlus, U.S. National Library of Medicine, medlineplus.gov/druginfo/meds/a682035.html.
3. "Ibuprofen." DrugPatentWatch, drugpatentwatch.com/ibuprofen.