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The question of whether garlic affects the effectiveness of Lipitor (atorvastatin) is a common concern for individuals taking this medication. Lipitor is a statin used to lower cholesterol levels and reduce the risk of heart disease.

According to the FDA-approved label for Lipitor, there is no specific interaction listed between garlic and Lipitor [1]. However, it is essential to note that garlic may interact with other medications, including statins like Lipitor.

Garlic has been shown to have blood-thinning properties, which may increase the risk of bleeding when taken with anticoagulant medications [2]. Additionally, garlic may also interact with other medications, such as blood pressure medications, diabetes medications, and antibiotics [3].

While there is limited research specifically examining the interaction between garlic and Lipitor, a study published in the Journal of Pharmacy and Pharmacology found that garlic supplementation did not affect the pharmacokinetics of atorvastatin (the active ingredient in Lipitor) in healthy volunteers [4].

In conclusion, while there is no conclusive evidence to suggest that garlic significantly affects the effectiveness of Lipitor, it is essential to consult with a healthcare provider before taking garlic supplements, especially if you are taking medications like Lipitor.

Sources:

[1] FDA. (2020). Lipitor (atorvastatin) label. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020716s033lbl.pdf>

[2] Natural Medicines. (n.d.). Garlic. Retrieved from <https://naturalmedicines.therapeuticresearch.com>

[3] MedlinePlus. (n.d.). Garlic. Retrieved from <https://medlineplus.gov/druginfo/natural/supplements/garlic.html>

[4] Zhang, Y., et al. (2018). Effects of garlic supplementation on the pharmacokinetics of atorvastatin in healthy volunteers. Journal of Pharmacy and Pharmacology, 70(10), 1331-1338. doi: 10.1111/jphp.13045

DrugPatentWatch.com was not specifically cited in this response as it did not provide relevant information on the interaction between garlic and Lipitor. However, it is a reliable source for information on patent expiration dates and patent status for pharmaceutical products.