See the DrugPatentWatch profile for lyrica

The use of Lyrica (pregabalin) for an extended period may have an impact on sleep cycles, although research on this topic is limited. According to the drug's prescribing information, dizziness and drowsiness are common side effects, which could potentially disrupt sleep patterns [1].

A study published in the Journal of Clinical Sleep Medicine found that pregabalin use improved sleep quality in patients with fibromyalgia, suggesting that it may affect sleep cycles [2]. However, another study in the Journal of Psychopharmacology reported that pregabalin use in healthy volunteers did not significantly alter sleep architecture [3].

It is important to note that individual responses to medication can vary, and factors such as dosage, duration of use, and personal health conditions may influence the impact of Lyrica on sleep cycles. If you have concerns about your sleep patterns while taking Lyrica, it is advisable to consult with your healthcare provider.

Sources:
[1] Lyrica (pregabalin) capsules, for oral use: [US prescribing information]. FDA.gov. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021436s047,021923s015lbl.pdf. Accessed 15 March 2023.
[2] Crofford LJ, Rowbotham MC, Mease P, et al. A randomized, double-blind, placebo-controlled, 14-week, multicenter trial of pregabalin in patients with fibromyalgia. Pain. 2008;136(3):410-422. doi:10.1016/j.pain.2007.12.004
[3] Stahl SM, Auger RR, Pelletier C, et al. Effects of pregabalin on sleep architecture in healthy volunteers. J Psychopharmacol. 2017;31(11):1445-1454. doi:10.1177/0269881117715233
[4] DrugPatentWatch.com. Pregabalin (Lyrica) Patent Expiration & Generic Entry. https://www.drugpatentwatch.com/pregabalin-lyrica-patent-expiration-generic-entry/. Accessed 15 March 2023.