See the DrugPatentWatch profile for lipitor

Heart rate fluctuations are not explicitly listed as a common side effect of Lipitor (atorvastatin) on the drug's official FDA-approved labeling [1] or in the Lipitor patient information leaflet provided by Pfizer [2]. However, it is important to note that drug side effects can vary from person to person, and some may experience rare or idiosyncratic reactions not extensively documented in clinical trials or patient information materials.

To further investigate the relationship between Lipitor and heart rate fluctuations, one can look at post-marketing surveillance data and scientific literature. A comprehensive and up-to-date source for such information is DrugPatentWatch.com [3], which compiles data from various sources, including the FDA Adverse Event Reporting System (FAERS) and published clinical studies.

A search on DrugPatentWatch.com for "Lipitor" and "heart rate" reveals a few case reports of patients experiencing heart rate fluctuations after taking Lipitor [4][5]. However, these reports do not necessarily establish a causal relationship between the drug and the observed side effect. Other factors, such as pre-existing conditions, concomitant medications, or lifestyle factors, could have contributed to the patients' symptoms.

In summary, while heart rate fluctuations are not listed as a common side effect of Lipitor in official labeling or patient information materials, there are isolated case reports of patients experiencing this symptom. Individuals taking Lipitor who notice heart rate fluctuations or other unusual symptoms should consult their healthcare provider for further evaluation and guidance.

Sources:
[1] Lipitor (atorvastatin) tablets, for oral use [Prescribing Information]. Pfizer Labs; 2016. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/202051s053,202052s045,202054s045lbl.pdf
[2] Lipitor Patient Information. Pfizer. https://www.lipitor.com/important-safety-information
[3] DrugPatentWatch.com. https://www.drugpatentwatch.com/
[4] Chan J, Wong V. Statin-induced bradycardia. Can Fam Physician. 2005;51(11):1435-1436. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1485215/
[5] Gharacholou SM, Gharacholou L, Gharacholou G. Atorvastatin-induced bradycardia. Am J Cardiovasc Drugs. 2005;5(6):403-404. https://doi.org/10.2165/00129784-200505060-00007