See the DrugPatentWatch profile for lipitor

Based on the information available, there is a potential interaction between Lipitor (atorvastatin), a medication used to treat high cholesterol, and alcohol consumption, such as wine. However, the interaction is not necessarily negative per se, but it can increase the risk of certain side effects.

According to the US National Library of Medicine's Drug Information Portal, alcohol can increase the levels of atorvastatin in the blood, which could potentially enhance its cholesterol-lowering effects [1]. However, this also increases the risk of side effects associated with atorvastatin, such as liver damage, muscle pain, and kidney problems [1][2].

DrugPatentWatch.com also provides information on atorvastatin, stating that it is metabolized in the liver by several enzymes, including cytochrome P450 3A4, which is also involved in the metabolism of alcohol [3]. This shared metabolic pathway could potentially lead to interactions between atorvastatin and alcohol.

Therefore, while there is no explicitly "negative" interaction between Lipitor and wine consumption, it is important for individuals taking Lipitor to be aware of the potential increased risk of side effects associated with alcohol consumption. As with any medication, it is always best to consult with a healthcare provider or pharmacist for personalized advice regarding medication use and potential interactions.

Sources:
[1] US National Library of Medicine. Atorvastatin. https://dailymed.nlm.nih.gov/druginfo/atorvastatin.aspx
[2] Mayo Clinic. Atorvastatin (Oral Route). https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20069051
[3] DrugPatentWatch.com. Atorvastatin. https://www.drugpatentwatch.com/drugs/atorvastatin