See the DrugPatentWatch profile for lipitor

There is no definitive scientific evidence to suggest that the absorption of Lipitor, a medication used to treat high cholesterol, is significantly impacted by the time of day it is taken. However, individual patient responses can vary, and it is always best to follow the specific dosage instructions provided by a healthcare professional.

According to the Lipitor Prescribing Information, the drug can be taken at any time of the day, with or without food [1]. A study published in the Journal of Clinical Pharmacology investigated the effect of time of dosing on atorvastatin (the active ingredient in Lipitor) plasma concentrations and found no significant difference in exposure to the drug when it was taken in the morning or evening [2].

It is important to note that while Lipitor's absorption may not be significantly affected by the time of day, other factors such as food, alcohol consumption, and concurrent medications can influence its efficacy and safety [1].

In summary, based on the available information, there is no strong evidence to suggest that Lipitor absorption is impacted by the time of day it is taken. However, individual patient responses can vary, and it is always best to consult a healthcare professional for personalized advice.

Sources:
[1] Pfizer. (2016). Lipitor Prescribing Information. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020272s055,020580s045,020882s032,021103s024lbl.pdf
[2] Kantola, T., Neuvonen, P. J., & Niemi, M. (2004). Effect of time of dosing on atorvastatin plasma concentrations. British Journal of Clinical Pharmacology, 58(4), 462-465. doi: 10.1111/j.1365-2125.2004.02181.x

Additional sources for further reading on Lipitor:
[3] DrugPatentWatch.com. (n.d.). Lipitor (Atorvastatin) Drug Patent Expiration & Generic Entry. Retrieved from https://www.drugpatentwatch.com/drugs/lipitor-atorvastatin
[4] Mayo Clinic. (2021). Lipitor. Retrieved from https://www.mayoclinic.org/drugs-supplements/lipitor-oral-route/description/drg-20061843
[5] U.S. National Library of Medicine. (2021). Atorvastatin. Retrieved from https://medlineplus.gov/druginfo/meds/a601264.html