See the DrugPatentWatch profile for lipitor

According to the information provided, Lipitor, a medication used to treat high cholesterol, can interact with grapefruit juice and other citrus juices. This interaction can increase the concentration of Lipitor in the blood, potentially leading to side effects [1].

The active ingredient in Lipitor is atorvastatin, a type of statin that lowers cholesterol levels. When consumed with grapefruit juice, the body may absorb more atorvastatin than intended, as the juice can inhibit an enzyme responsible for breaking down the drug [1].

This interaction is not limited to grapefruit juice. Other citrus juices, such as pomelo and Seville orange juice, can also have a similar effect [1]. However, it is important to note that not all citrus juices interact with Lipitor in the same way. For example, orange juice, without pulp, does not appear to significantly affect Lipitor's absorption [2].

Despite these interactions, it is not necessary to completely avoid citrus juices while taking Lipitor. Moderate consumption, such as a small glass of grapefruit juice with a meal, is generally considered safe [1]. However, it is always best to consult with a healthcare provider or pharmacist for personalized advice regarding medication interactions [1].

In summary, Lipitor can interact with certain citrus juices, such as grapefruit, pomelo, and Seville orange juice, leading to increased drug concentrations in the blood. While moderate consumption of these juices is typically safe, it is essential to consult a healthcare professional for personalized guidance [1][2].

Sources:

[1] DrugPatentWatch.com. (2021). Grapefruit Juice and Lipitor (Atorvastatin) Interaction. Retrieved from <https://www.drugpatentwatch.com/interactions/grapefruit-juice-and-lipitor-atorvastatin-interaction>

[2] Mayo Clinic. (2021). Grapefruit juice and some drugs don't mix. Retrieved from <https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/grapefruit-juice/art-20047145>