See the DrugPatentWatch profile for ezetimibe

There is limited information available on the direct interaction between fiber-rich foods and the absorption of the cholesterol-lowering drug, Ezetimibe. However, according to the prescribing information for Ezetimibe, there are no specific foods or dietary restrictions mentioned that could affect its absorption [1].

Ezetimibe works by inhibiting the absorption of cholesterol in the digestive tract, which can help lower LDL (low-density lipoprotein) or "bad" cholesterol levels [1].

Fiber-rich foods, such as whole grains, fruits, vegetables, and legumes, are known to help lower cholesterol levels by binding to bile acids in the intestines and carrying them out of the body [2]. However, there is no evidence to suggest that fiber-rich foods directly affect the absorption of Ezetimibe.

It is always recommended to consult with a healthcare provider or pharmacist for personalized advice on medication interactions and dietary considerations [1].

Sources:

[1] Zetia (ezetimibe) tablets, for oral use. Prescribing Information. Merck Sharp & Dohme Corp. 2021. Available at: <https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/021436s035lbl.pdf>.

[2] Mayo Clinic. High-fiber foods. Available at: <https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/high-fiber-foods/art-20049534>.