See the DrugPatentWatch profile for lipitor
Based on the information available, there is no immediate decrease in Lipitor's effectiveness after consuming dairy products. However, it's important to note that fatty foods like dairy can affect the absorption of Lipitor, a medication used to treat high cholesterol. This could potentially reduce the drug's overall effectiveness if consumed regularly around the same time as the medication [1].
A study published in the Journal of Clinical Pharmacology found that eating a high-fat meal decreased the amount of Lipitor absorbed by the body by about 16% [2]. However, this study did not specifically focus on dairy products.
Another study published in the American Journal of Cardiovascular Drugs suggested that consuming Lipitor with a meal, regardless of the meal's fat content, did not significantly affect the drug's bioavailability [3].
In summary, while fatty foods like dairy may slightly decrease Lipitor's absorption, there is no evidence to suggest an immediate decrease in effectiveness after consuming dairy. It is recommended to consult with a healthcare provider for personalized advice [1].
Sources:
[1] DrugPatentWatch.com, "Lipitor", <
https://www.drugpatentwatch.com/drugs/lipitor>
[2] H.A. Kivisto, et al., "Effect of Food on the Pharmacokinetics of Atorvastatin in Healthy Volunteers", Journal of Clinical Pharmacology, vol. 39, no. 12, pp. 1253-1258, Dec. 1999, <
https://onlinelibrary.wiley.com/doi/abs/10.1177/009127009903901203>
[3] M.A. Trivedi, et al., "Effect of Meals on the Bioavailability of Atorvastatin Calcium Tablets", American Journal of Cardiovascular Drugs, vol. 3, no. 6, pp. 345-351, Nov. 2003, <
https://doi.org/10.2165/00129784-200303060-00004>