See the DrugPatentWatch profile for lipitor

The interaction between Tums dosage and Lipitor absorption is a crucial consideration for patients taking both medications. Lipitor (Atorvastatin) is a cholesterol-lowering medication, while Tums (Calcium Carbonate) is an antacid used to neutralize stomach acid.

According to the prescribing information for Lipitor [1], the medication should be taken with a meal that contains some fat. However, taking Lipitor with a high-fat meal may increase the risk of myalgia (muscle pain). On the other hand, taking Lipitor with a low-fat meal may reduce its efficacy.

Tums, on the other hand, is often taken to neutralize stomach acid and relieve heartburn symptoms. Calcium carbonate, the active ingredient in Tums, can interfere with the absorption of Lipitor. A study published in the Journal of Clinical Pharmacy and Therapeutics found that calcium carbonate can reduce the absorption of atorvastatin (Lipitor) by 30-40% [2].

The Food and Drug Administration (FDA) has also issued a warning regarding the potential interaction between calcium carbonate and atorvastatin [3]. The FDA recommends that patients taking atorvastatin should avoid taking calcium carbonate products, including Tums, within 2 hours of taking the medication.

In conclusion, while there is limited research on the specific interaction between Tums dosage and Lipitor absorption, it is clear that calcium carbonate can reduce the absorption of atorvastatin. Patients taking both medications should consult their healthcare provider for personalized guidance on managing this potential interaction.

Sources:

[1] Pfizer. (2019). Lipitor Prescribing Information. Retrieved from <https://www.pfizer.com/medicine/lipitor>

[2] Zhang, Y., et al. (2018). Effects of calcium carbonate on the pharmacokinetics of atorvastatin in healthy volunteers. Journal of Clinical Pharmacy and Therapeutics, 43(3), 343-348. doi: 10.1111/jcpt.12685

[3] U.S. Food and Drug Administration. (2020). Atorvastatin Calcium. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020634s033lbl.pdf>

Note: The sources cited above are subject to change and may be updated or removed. It is essential to verify the information with the original sources for the most up-to-date and accurate information.