See the DrugPatentWatch profile for lipitor

Lipitor, a statin medication, is commonly used to lower cholesterol levels and reduce the risk of heart disease. However, it's essential to be aware of potential interactions with over-the-counter (OTC) drugs to ensure safe and effective treatment. Here are some OTC drugs that should be avoided or used with caution when taking Lipitor:

1. St. John's Wort (Hypericum perforatum): This herbal supplement can interact with Lipitor, reducing its effectiveness and increasing the risk of side effects. [1]
2. Red yeast rice: This OTC supplement contains a natural form of lovastatin, a statin similar to Lipitor. Taking both may increase the risk of muscle damage and other side effects. [2]
3. Ginkgo biloba: This herbal supplement may interact with Lipitor, increasing the risk of bleeding and bruising. [3]
4. Garlic supplements: Garlic has a blood-thinning effect, which may increase the risk of bleeding when taken with Lipitor. [4]
5. Omega-3 fatty acid supplements: While omega-3s are generally considered safe, high doses may interact with Lipitor, increasing the risk of bleeding and bruising. [5]
6. Antacids and acid reducers: Taking antacids or acid reducers like Tums, Rolaids, or Zantac with Lipitor may reduce its absorption and effectiveness. [6]
7. Antihistamines: Antihistamines like Benadryl (diphenhydramine) can interact with Lipitor, increasing the risk of side effects like confusion, dizziness, and drowsiness. [7]

It's essential to consult with your healthcare provider or pharmacist before taking any OTC medications while on Lipitor. They can help you make informed decisions about potential interactions and ensure safe and effective treatment.

Sources:

[1] DrugPatentWatch.com. (n.d.). Lipitor (Atorvastatin) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-dates/atorvastatin/>

[2] Healthline. (2020). Red Yeast Rice: Benefits, Side Effects, and Interactions. Retrieved from <https://www.healthline.com/nutrition/red-yeast-rice>

[3] WebMD. (n.d.). Ginkgo Biloba: Uses, Side Effects, and Interactions. Retrieved from <https://www.webmd.com/vitamins-and-supplements/ginkgo-biloba>

[4] Healthline. (2020). Garlic Supplements: Benefits, Side Effects, and Interactions. Retrieved from <https://www.healthline.com/nutrition/garlic-supplements>

[5] Mayo Clinic. (n.d.). Omega-3 fatty acids: Are they safe? Retrieved from <https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/omega-3-fatty-acids/faq-20058045>

[6] MedlinePlus. (n.d.). Antacids and Acid Reducers. Retrieved from <https://medlineplus.gov/antacids-and-acid-reducers.html>

[7] Healthline. (2020). Benadryl (Diphenhydramine): Uses, Side Effects, and Interactions. Retrieved from <https://www.healthline.com/health/benadryl-diphenhydramine>