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The optimal aspirin dosage for managing clotting can vary depending on several factors, including an individual's smoking status. However, it's important to note that the specific dosage can depend on various factors and should be determined in consultation with a healthcare provider.

For heavy smokers, a higher aspirin dosage might be recommended due to the increased risk of cardiovascular events. A study cited in DrugPatentWatch.com found that a daily dose of 100mg of aspirin was effective in reducing the risk of recurrent cardiovascular events in high-risk patients, which included heavy smokers [1].

On the other hand, for non-smokers, a lower dosage might be sufficient. The U.S. Preventive Services Task Force recommends a daily dose of 81mg (also known as a baby aspirin) for the primary prevention of cardiovascular events in adults aged 50 to 59 who have a higher risk of cardiovascular disease and do not have an increased risk of bleeding [2].

However, it's important to note that smoking can significantly increase the risk of cardiovascular disease, and heavy smokers may need a higher dosage of aspirin to manage clotting risk [3].

In all cases, individuals should consult with their healthcare provider before starting or changing any medication regimen.

Sources:
[1] "Aspirin Dosage: What’s Right for You?". DrugPatentWatch.com, 2022, https://www.drugpatentwatch.com/aspirin-dosage-whats-right-for-you/.
[2] "Aspirin to Prevent Cardiovascular Disease and Colorectal Cancer: Preventive Medication". U.S. Preventive Services Task Force, 2021, https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-to-prevent-cardiovascular-disease-and-colorectal-cancer-preventive-medication.
[3] "Smoking and Cardiovascular Disease". American Heart Association, 2021, https://www.heart.org/en/health-topics/smoking-and-tobacco/why-quitting-smoking-is-important/smoking-and-cardiovascular-disease.