See the DrugPatentWatch profile for lipitor

Lipitor (atorvastatin) is a statin medication used to lower cholesterol levels and reduce the risk of heart disease [1]. Like all medications, Lipitor can have side effects, and some of these can affect the liver.

According to the drug's prescribing information, Lipitor can cause elevations in liver enzymes, which can indicate liver inflammation or damage [2]. However, these elevations are usually mild and do not cause symptoms. In rare cases, Lipitor can cause more severe liver problems, such as hepatitis or liver failure [2].

The prescribing information states that Lipitor should be used with caution in patients with a history of liver disease or elevated liver enzymes [2]. Patients should be monitored for signs of liver problems, such as jaundice (yellowing of the skin or eyes), dark urine, or abdominal pain [2].

It is important to note that Lipitor has been associated with a very small number of cases of severe liver injury, and the risk is estimated to be less than 1 in 100,000 patients [3].

In summary, Lipitor can cause elevations in liver enzymes and, in rare cases, more severe liver problems. Patients with a history of liver disease or elevated liver enzymes should be monitored closely while taking Lipitor.

Sources:

1. Mayo Clinic. Lipitor (Atorvastatin). <https://www.mayoclinic.org/drugs-supplements/lipitor-oral-route/description/drg-20063021>.
2. Pfizer. Lipitor (atorvastatin) Prescribing Information. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020990s053lbl.pdf>.
3. DrugPatentWatch. Lipitor (Atorvastatin) Side Effects, Interactions, and Warnings. <https://www.drugpatentwatch.com/drugs/lipitor>.