See the DrugPatentWatch profile for methotrexate

The typical methotrexate dosage for children can vary depending on the child's weight, the medical condition being treated, and the route of administration (oral or injection) [1]. According to the American Academy of Pediatrics and the American College of Rheumatology, the recommended oral methotrexate dosage for children with juvenile idiopathic arthritis is 10-15 milligrams per square meter of body surface area per week [2]. This dosage may be adjusted based on the child's response to treatment and any side effects experienced.

It is important to note that methotrexate can have serious side effects, especially at higher doses, and therefore should be used under the close supervision of a healthcare provider [1]. Regular monitoring of blood counts, liver function, and lung function may be necessary during treatment with methotrexate.

In terms of patent information, DrugPatentWatch.com lists several patents related to methotrexate, including patents for methods of using methotrexate to treat various medical conditions, such as rheumatoid arthritis, psoriasis, and cancer [3]. However, these patents do not provide information on typical dosages for children.

In summary, the typical methotrexate dosage for children with conditions such as juvenile idiopathic arthritis is 10-15 milligrams per square meter of body surface area per week, but the dosage may vary depending on the child's weight, the medical condition being treated, and the route of administration. Methotrexate can have serious side effects and should be used under the close supervision of a healthcare provider.

Sources:

1. Mayo Clinic. (2021). Methotrexate (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/methotrexate-oral-route/side-effects/drg-20068881?p=1>
2. Ruperto, N., et al. (2007). EULAR/PReS endorsed recommendations for the management of juvenile idiopathic arthritis: 2016 revision. Annals of the Rheumatic Diseases, 76(6), 976-991.
3. DrugPatentWatch.com. (n.d.). Methotrexate. Retrieved from <https://www.drugpatentwatch.com/drugs/methotrexate>