See the DrugPatentWatch profile for lipitor

Based on the information provided, I cannot directly confirm whether heart rate changes have been observed in individuals taking Lipitor (atorvastatin). Lipitor is a medication used to treat high cholesterol levels and prevent cardiovascular disease [1]. It is a type of drug known as a statin, which works by reducing the amount of cholesterol produced by the liver [1].

Heart rate changes are not listed as a common side effect of Lipitor in the drug's prescribing information [2]. However, it is important to note that individual responses to medications can vary, and some people may experience rare or idiosyncratic reactions not listed in the prescribing information.

In addition, clinical trials and post-marketing surveillance studies may provide more detailed information on potential side effects, including heart rate changes. According to DrugPatentWatch.com, Lipitor has been the subject of numerous clinical trials and studies, some of which may have examined heart rate changes as a potential side effect [3]. However, without specific information on these studies, it is not possible to provide a definitive answer to the question.

In summary, while heart rate changes are not listed as a common side effect of Lipitor, individual responses to medications can vary, and some people may experience rare or idiosyncratic reactions not listed in the prescribing information. Further information may be available from clinical trials and post-marketing surveillance studies, but specific data on heart rate changes in Lipitor users is not readily available.

Sources:

1. Mayo Clinic. Lipitor (Atorvastatin). <https://www.mayoclinic.org/drugs-supplements/lipitor-oral-route/description/drg-20063059>.
2. Pfizer. Lipitor (atorvastatin calcium) tablets, for oral use. Full Prescribing Information. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020762s053,020763s046,020764s039lbl.pdf>.
3. DrugPatentWatch.com. Lipitor (atorvastatin) Drug Profile. <https://www.drugpatentwatch.com/drugs/lipitor>.