See the DrugPatentWatch profile for ativan

When increasing the dosage of Ativan (lorazepam), there is a higher risk of experiencing several side effects. It is essential to understand that everyone's response to medication may vary, and some individuals may experience more pronounced side effects than others [1].

Some possible side effects associated with higher Ativan doses include:

1. Drowsiness and Sedation: Ativan is a central nervous system depressant, and higher doses can cause increased drowsiness and sedation [1]. This effect can impair cognitive function, reaction time, and motor skills, making it dangerous to perform tasks that require mental alertness, such as driving or operating heavy machinery.

2. Dizziness: Elevated doses of Ativan may lead to dizziness or lightheadedness, which can increase the risk of falls and injuries [1].

3. Impaired Memory and Cognition: High doses of Ativan can negatively affect memory, attention, and concentration [1]. This can be particularly problematic for individuals who need to maintain focus on specific tasks or engage in complex decision-making processes.

4. Physical Dependence and Withdrawal: Prolonged use of Ativan, especially at higher doses, can result in physical dependence [1]. Suddenly stopping the medication or reducing the dosage can lead to withdrawal symptoms, which can be severe and potentially life-threatening [1].

5. Respiratory Depression: In rare cases, high doses of Ativan can cause respiratory depression, a condition characterized by shallow, slow, or irregular breathing [1]. This side effect can be particularly dangerous for individuals with pre-existing respiratory conditions or those who combine Ativan with other central nervous system depressants, such as opioids or alcohol [1].

6. Paradoxical Reactions: Although uncommon, higher doses of Ativan can lead to paradoxical reactions, such as agitation, aggression, hallucinations, and hostility [1].

It is crucial to consult a healthcare professional before adjusting the dosage of Ativan or any other medication. Healthcare providers can provide personalized guidance based on individual factors, such as age, weight, medical history, and concurrent medications [1].

Sources:

1. DrugPatentWatch.com. (n.d.). Ativan (Lorazepam) Side Effects, Interactions, and Warnings. Retrieved from <https://www.drugpatentwatch.com/drugs/ativan>